Kaitlyn Bosch

Vitamin C selectively kills <i>KRAS</i> and <i>BRAF</i> mutant colorectal cancer cells by targeting GAPDH

Jihye Yun, Edouard Mullarky, Changyuan Lu et al. · Science · 2015 · 910 citations

Medicine, Cancer Biology, Oncology +14

High-fructose corn syrup enhances intestinal tumor growth in mice

Marcus D. Goncalves, Changyuan Lu, Jordan Tutnauer et al. · Science · 2019 · 379 citations

Medicine, Nutritional Sciences, Oncology +17

Deletion of the gene <i>Pip4k2c</i> , a novel phosphatidylinositol kinase, results in hyperactivation of the immune system

Hyeseok Shim, Chuan Wu, Shivan Ramsamooj et al. · Proceedings of the National Academy of Sciences · 2016 · 64 citations · Full text

Life Sciences, Cancer Biology, Immunology +14

AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells

Kaitlyn M. Cahuzac, Abigail Lubin, Kaitlyn Bosch et al. · Cell Reports · 2023 · 48 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

A local tumor microenvironment acquired super-enhancer induces an oncogenic driver in colorectal carcinoma

Royce Zhou, Jia Xu, Tiphaine Martin et al. · Nature Communications · 2022 · 45 citations · Full text

Medicine, Cancer Biology, Oncology +17