Salt-responsive gut commensal modulates TH17 axis and disease

Nicola Wilck, Mariana Matus, Sean M. Kearney, +35

Nature

Autoimmune DiseaseMucosal ImmunologyImmunologyGastroenterologyGut-organ Axis +5

Induction and molecular signature of pathogenic TH17 cells

Youjin Lee, Amit Awasthi, Nir Yosef, +10

Nature Immunology

Autoimmune DiseaseT-regulatory CellPathogenesisImmunologyAutoimmunity +4

Induction of pathogenic TH17 cells by inducible salt-sensing kinase SGK1

Chuan Wu, Nir Yosef, Theresa Thalhamer, +5

Nature

InflammationCytokineSignal TransductionImmunologyImmune Regulation +9

Dynamic regulatory network controlling TH17 cell differentiation

Nir Yosef, Alex K. Shalek, Jellert T. Gaublomme, +20

Nature

Single-Cell Genomics Unveils Critical Regulators of Th17 Cell Pathogenicity

Jellert T. Gaublomme, Nir Yosef, Youjin Lee, +10

Cell

Autoimmune DiseaseSingle Cell SequencingMedicineT-regulatory CellImmunology +5

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

Moshe Biton, Adam L. Haber, Noga Rogel, +26

Cell

InflammationDevelopmental BiologyMucosal ImmunologyLymphocyte DevelopmentT-regulatory Cell +6

Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis

Jun Wei, Lingyun Long, Kai Yang, +8

Nature Immunology

Cell AutophagyMitophagySignal TransductionAutoimmune DiseaseT-regulatory Cell +12

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

Chao Wang, Nir Yosef, Jellert T. Gaublomme, +19

Cell

Molecular ImmunologyImmunologyAutoimmunityCd4 T Cell ResponsesCellular Immune Response +4

Galectin-9-CD44 Interaction Enhances Stability and Function of Adaptive Regulatory T Cells

Chuan Wu, Theresa Thalhamer, Rafael Freitas de Oliveira França, +7

Immunity

Autoimmune DiseaseAdaptive Immune SystemT-regulatory CellImmunologyRegulatory T Cells +7

Gut-Innervating Nociceptor Neurons Regulate Peyer’s Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense

Nicole Y. Lai, Melissa A. Musser, Felipe A. Pinho‐Ribeiro, +24

Cell

Sfb LevelsMucosal ImmunologySynaptic SignalingMicrobial PathogensPatch Microfold Cells +10