Hyeseok Shim

A Drosophila Resource of Transgenic RNAi Lines for Neurogenetics

Jian‐Quan Ni, Luping Liu, Richard Binari et al. · Genetics · 2009 · 331 citations · Full text

Developmental Genetics, Genetics, Gypsy Insulator Sequences +12

Depletion of a Putatively Druggable Class of Phosphatidylinositol Kinases Inhibits Growth of p53-Null Tumors

Brooke M. Emerling, Jonathan Hurov, George Poulogiannis et al. · Cell · 2013 · 194 citations · Full text

Tumor Biology, Glioma, Medicine +10

Deletion of the gene <i>Pip4k2c</i> , a novel phosphatidylinositol kinase, results in hyperactivation of the immune system

Hyeseok Shim, Chuan Wu, Shivan Ramsamooj et al. · Proceedings of the National Academy of Sciences · 2016 · 64 citations · Full text

Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors

Sindhu Carmen Sivakumaren, Hyeseok Shim, Tinghu Zhang et al. · Cell chemical biology · 2020 · 53 citations · Full text

Drug Targeting, Drug Target, Receptor Tyrosine Kinase +5

Discovery and Structure–Activity Relationship Study of ( <i>Z</i> )-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors

Theresa Manz, Sindhu Carmen Sivakumaren, Fleur M. Ferguson et al. · Journal of Medicinal Chemistry · 2020 · 25 citations · Full text