Patricia Imbach‐Weese

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

Pascal Furet, Vito Guagnano, Robin A. Fairhurst et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 470 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

The First Class of Small Molecules Potently Disrupting the YAP‐TEAD Interaction by Direct Competition

Pascal Furet, Vincent Bordas, Mickaël Le Douget et al. · ChemMedChem · 2022 · 43 citations

Medicine, Oncology, Pharmacology +17

Discovery of New Binders for DCAF1, an Emerging Ligase Target in the Targeted Protein Degradation Field

Anna Vulpetti, Philipp Holzer, Niko Schmiedeberg et al. · ACS Medicinal Chemistry Letters · 2023 · 38 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Podocyte EphB4 signaling helps recovery from glomerular injury

Monika Wnuk, Ruslan Hlushchuk, Mathilde Janot et al. · Kidney International · 2012 · 28 citations · Full text

Medicine, Cell Biology, Nephrology +16

Identification and optimisation of a 4′,5-bisthiazole series of selective phosphatidylinositol-3 kinase alpha inhibitors

Robin A. Fairhurst, Patricia Imbach‐Weese, Marc Gerspacher et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 21 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13