Daniel J. Anderson

RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth

Georgia Hatzivassiliou, Kyung Song, Ivana Yen et al. · Nature · 2010 · 1.6K citations · Full text

Signaling Pathway, Receptor Tyrosine Kinase, Mapk Pathway +8

Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7

Ingrid E. Wertz, Saritha Kusam, Cynthia Lam et al. · Nature · 2011 · 806 citations

Protein Function, Medicine, Immune Checkpoint Inhibitor +9

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

Till Maurer, Lindsay S. Garrenton, Angela Oh et al. · Proceedings of the National Academy of Sciences · 2012 · 621 citations · Full text

Distinct Pocket, Molecular Biology, Ras Gene +21

Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)

H Zhang, J Chen, Sajid Khan Tahir et al. · Cell Death and Disease · 2015 · 427 citations · Full text

Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis

Daniel J. Anderson, Ronan Le Moigne, Stevan Djakovic et al. · Cancer Cell · 2015 · 392 citations · Full text

Protein Function, Medicine, Natural Sciences +13