Concepedia
Statistics
Publications
15
Citations
1.1K
H-Index
12
Active since
2006
Affiliations
Essa Pharma (United States)(Current)
Aptose Biosciences (United States)
BC Cancer Agency
University of British Columbia
Centre National de la Recherche Scientifique
Ronan Le Moigne is an author at Essa Pharma (United States) specializing in medicine, pharmacology, and oncology.
Top concepts
MedicinePharmacologyUrologyOncologyDrug DiscoveryCancer ResearchPharmacotherapyCell BiologyTumor BiologyCancer Therapy
Publications per year
2006–2023
Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis
Daniel J. Anderson, Ronan Le Moigne, Stevan Djakovic et al. · Cancer Cell · 2015 · 392 citations · Full text
Protein Function, Medicine, Natural Sciences +13
Discovery of a First-in-Class, Potent, Selective, and Orally Bioavailable Inhibitor of the p97 AAA ATPase (CB-5083)
Han-Jie Zhou, Jinhai Wang, Bing Yao et al. · Journal of Medicinal Chemistry · 2015 · 184 citations · Full text
Apoptosis, Cell Death, Protein Homeostasis +20
The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma
Ronan Le Moigne, Blake T. Aftab, Stevan Djakovic et al. · Molecular Cancer Therapeutics · 2017 · 111 citations
Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA
Delphine Poncet, Anne‐Laure Pauleau, György Szabadkai et al. · The Journal of Cell Biology · 2006 · 97 citations · Full text
CB-6644 Is a Selective Inhibitor of the RUVBL1/2 Complex with Anticancer Activity
Victoria A. Assimon, Yangzhong Tang, Jesse D. Vargas et al. · ACS Chemical Biology · 2019 · 91 citations
Cancer Biology, Tumor Biology, Molecular Pharmacology +17
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