Ronald J. Heemstra

Discovery of a Series of Imidazo[4,5-<i>b</i>]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-γ

Agustin Casimiro‐Garcia, Gary F. Filzen, Declan Flynn et al. · Journal of Medicinal Chemistry · 2011 · 52 citations · Full text

Progress in the discovery of Factor Xa inhibitors

Agustin Casimiro‐Garcia, Danette A. Dudley, Ronald J. Heemstra et al. · Expert Opinion on Therapeutic Patents · 2006 · 27 citations

Molecular Pharmacology, Medicinal Chemistry, Thrombosis +15

Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-γ

Agustin Casimiro‐Garcia, Ronald J. Heemstra, Christopher F. Bigge et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 26 citations · Full text

Biochemistry, Medicine, Dual Activity +7

Exploration of 4,4-disubstituted pyrrolidine-1,2-dicarboxamides as potent, orally active Factor Xa inhibitors with extended duration of action

Chad A. Van Huis, Agustin Casimiro‐Garcia, Christopher F. Bigge et al. · Bioorganic & Medicinal Chemistry · 2009 · 20 citations · Full text

Medicinal Chemistry, Medicine, Pharmacological Agent +8

Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs)

Jon‐Paul Strachan, David C. Kombo, Anatoly Mazurov et al. · European Journal of Medicinal Chemistry · 2014 · 10 citations · Full text