Danette A. Dudley

Discovery of (<i>S</i>)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1<i>H</i>-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1<i>H</i>)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development

James F. Blake, Michael Burkard, Jocelyn Chan et al. · Journal of Medicinal Chemistry · 2016 · 156 citations · Full text

Erk Kinase Activity, Cellular Pharmacology, Tumor Biology +20

Design, Synthesis, and Biological Activity of Potent and Selective Inhibitors of Blood Coagulation Factor Xa

J. Adam Willardsen, Danette A. Dudley, Wayne L. Cody et al. · Journal of Medicinal Chemistry · 2004 · 121 citations

A versatile copper-catalyzed coupling reaction of pyridin-2(1H)-ones with aryl halides

Kevin J. Filipski, Jeffrey T. Kohrt, Agustin Casimiro‐Garcia et al. · Tetrahedron Letters · 2006 · 56 citations

Aryl Halides, Chemical Engineering, Cross-coupling Reaction +7

Discovery of a Series of Imidazo[4,5-<i>b</i>]pyridines with Dual Activity at Angiotensin II Type 1 Receptor and Peroxisome Proliferator-Activated Receptor-γ

Agustin Casimiro‐Garcia, Gary F. Filzen, Declan Flynn et al. · Journal of Medicinal Chemistry · 2011 · 52 citations · Full text

Rational Design, Synthesis, and Biological Activity of Benzoxazinones as Novel Factor Xa Inhibitors

Danette A. Dudley, Amy Bunker, Liguo Chi et al. · Journal of Medicinal Chemistry · 2000 · 49 citations · Full text

Combinatorial Chemistry, Inappropriate Thrombus Formation, Organic Chemistry +17