Concepedia

Identification and pharmacological characterization of 3,6-diazabicyclo[3.1.1]heptane-3-carboxamides as novel ligands for the α4β2 and α6/α3β2β3 nicotinic acetylcholine receptors (nAChRs)

Jon‐Paul Strachan, David C. Kombo, Anatoly Mazurov, Ronald J. Heemstra, Balwinder S. Bhatti, Rao Akireddy, Srinivasa Murthy, Lan Miao, John E Jett, Jason D. Speake,

European Journal of Medicinal Chemistry · 2014 · 10 citations · 45 references

Open access

References

45

PROCHECK: a program to check the stereochemical quality of protein structures

Roman A. Laskowski, Malcolm W. MacArthur, D. S. Moss et al. · Journal of Applied Crystallography · 1993 · 24.4K citations

Protein Structures, Procheck Suite, Protein Assembly +14

Comparative Protein Modelling by Satisfaction of Spatial Restraints

Andrej Săli, Tom L. Blundell · Journal of Molecular Biology · 1993 · 13K citations

Engineering, Comparative Protein Modelling, Protein Folding +8

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11K citations

Development Settings, Pharmaceutical Science, Drug Target +8

Glide: A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy

Richard A. Friesner, Jay L. Banks, Robert B. Murphy et al. · Journal of Medicinal Chemistry · 2004 · 9.6K citations