Christopher A. Lipinski

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 1997 · 11.2K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Lead- and drug-like compounds: the rule-of-five revolution

Christopher A. Lipinski · Drug Discovery Today Technologies · 2004 · 6.1K citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 2012 · 3.7K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Increased Fibroblast Growth Factor-Inducible 14 Expression Levels Promote Glioma Cell Invasion via Rac1 and Nuclear Factor-κB and Correlate with Poor Patient Outcome

Nhan L. Tran, Wendy S. McDonough, Benjamin A. Savitch et al. · Cancer Research · 2006 · 189 citations

Life Sciences, Cancer Biology, Cell Biology +17

Quantitative Structure−Activity Relationships among Macrolide Antibacterial Agents:  In Vitro and in Vivo Potency against <i>Pasteurella multocida</i>

James W. McFarland, Cynthia M. Berger, S Froshauer et al. · Journal of Medicinal Chemistry · 1997 · 156 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15