Jason D. Speake

3D Molecular Descriptors Important for Clinical Success

David C. Kombo, Kartik Tallapragada, Rachit Jain et al. · Journal of Chemical Information and Modeling · 2012 · 122 citations

DNDI-6148: A Novel Benzoxaborole Preclinical Candidate for the Treatment of Visceral Leishmaniasis

Charles E. Mowbray, Stéphanie Braillard, Paul A. Glossop et al. · Journal of Medicinal Chemistry · 2021 · 64 citations · Full text

Systemic Administration of an Alpha-7 Nicotinic Acetylcholine Agonist Reverses Neuropathic Pain in Male Sprague Dawley Rats

Lisa C. Loram, Frederick R. Taylor, Keith A. Strand et al. · Journal of Pain · 2012 · 55 citations · Full text

Pain Therapy, Health Sciences, Pain Medicine +10

Regulation of Ingestive Behaviors in the Rat by GSK1521498, a Novel μ-Opioid Receptor-Selective Inverse Agonist

Diane M. Ignar, Aaron S. Goetz, Kimberly Nichols Noble et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 43 citations

Discovery of 3-(5-Chloro-2-furoyl)-3,7-diazabicyclo[3.3.0]octane (TC-6683, AZD1446), a Novel Highly Selective α4β2 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders

Anatoly Mazurov, Lan Miao, Balwinder S. Bhatti et al. · Journal of Medicinal Chemistry · 2012 · 33 citations · Full text

Psychotropic Medication, Peptide Science, Pharmacotherapy +20