Claire Jackson

Selective Class I Phosphoinositide 3-Kinase Inhibitors: Optimization of a Series of Pyridyltriazines Leading to the Identification of a Clinical Candidate, AMG 511

Mark H. Norman, Kristin L. Andrews, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2012 · 50 citations · Full text

Chemoprevention Strategy, Molecular Biology, Clinical Candidate +19

Structure-Based Design of a Novel Series of Potent, Selective Inhibitors of the Class I Phosphatidylinositol 3-Kinases

Adrian L. Smith, Noel D. D’Angelo, Yunxin Bo et al. · Journal of Medicinal Chemistry · 2012 · 49 citations · Full text

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies

Xavier Pépin, Leon Aarons, Yuya Wang et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2020 · 36 citations · Full text

Pharmacokinetic Modeling, Prediction Accuracy, Modelling Strategies +9

Control of Cerebellar Long-Term Potentiation by P-Rex-Family Guanine-Nucleotide Exchange Factors and Phosphoinositide 3-Kinase

Claire Jackson, Heidi C. E. Welch, Tomas C. Bellamy · PLoS ONE · 2010 · 26 citations · Full text

The discovery and optimization of aminooxadiazoles as potent Pim kinase inhibitors

Ryan P. Wurz, Liping H. Pettus, Claire Jackson et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 24 citations

Medicinal Chemistry, Biochemistry, Medicine +11