Heidi C. E. Welch

P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-Regulated Guanine-Nucleotide Exchange Factor for Rac

Heidi C. E. Welch, W. John Coadwell, Christian D. Ellson et al. · Cell · 2002 · 477 citations · Full text

Transcriptional Regulation, Signal Transduction, Molecular Regulation +8

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

Colin R. Lindsay, Samuel O. Lawn, Andrew D. Campbell et al. · Nature Communications · 2011 · 176 citations · Full text

Tumor Biology, Tumor Heterogeneity, Medicine +8

P-Rex1 Regulates Neutrophil Function

Heidi C. E. Welch, Alison M. Condliffe, Laura Milne et al. · Current Biology · 2005 · 175 citations · Full text

Inflammation, Signal Transduction, Molecular Physiology +7

Gβγs and the Ras binding domain of p110γ are both important regulators of PI3Kγ signalling in neutrophils

Sabine Suire, Alison M. Condliffe, Gail Ferguson et al. · Nature Cell Biology · 2006 · 169 citations

Inflammation, Signal Transduction, Molecular Physiology +9

Regulation of P-Rex1 by Phosphatidylinositol (3,4,5)-Trisphosphate and Gβγ Subunits

Kirsti Hill, Sonja Krugmann, Simon Andrews et al. · Journal of Biological Chemistry · 2004 · 125 citations · Full text

Rac-gef Activities, Molecular Physiology, Signal Transduction +15