Concepedia

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

Colin R. Lindsay, Samuel O. Lawn, Andrew D. Campbell, William J. Faller, Florian Rambow, Richard L. Mort, Paul Timpson, Ang Li, Patrizia Cammareri, Rachel A. Ridgway,

Nature Communications · 2011 · 180 citations · 29 references

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29

Mutations of the BRAF gene in human cancer

Helen Davies, Graham R. Bignell, Charles Cox et al. · Nature · 2002 · 10.7K citations

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Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

Keith T. Flaherty, Igor Puzanov, Kevin B. Kim et al. · New England Journal of Medicine · 2010 · 3.5K citations

, , +17

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

Gideon Bollag, Peter Hirth, James Tsai et al. · Nature · 2010 · 1.8K citations

, , +14

Kinase-Dead BRAF and Oncogenic RAS Cooperate to Drive Tumor Progression through CRAF

Sonja J. Heidorn, Carla Milagre, Steven R. Whittaker et al. · Cell · 2010 · 1.5K citations · Full text

, , +17

P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-Regulated Guanine-Nucleotide Exchange Factor for Rac

Heidi C. E. Welch, W. John Coadwell, Christian D. Ellson et al. · Cell · 2002 · 485 citations · Full text

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