Peter Hirth

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

Gideon Bollag, Peter Hirth, James Tsai et al. · Nature · 2010 · 1.8K citations

Medicine, Oncology, Pharmacology +14

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

James Tsai, John Tayu Lee, Weiru Wang et al. · Proceedings of the National Academy of Sciences · 2008 · 1.3K citations · Full text

Medicine, Oncology, Pharmacology +15

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

Yasunori Kasahara, Rubin M. Tuder, Laimute Taraseviciene‐Stewart et al. · Journal of Clinical Investigation · 2000 · 1.1K citations · Full text

Life Sciences, Cell Biology, Pharmacology +14

Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors

Moosa Mohammadi, Gerald McMahon, Li Sun et al. · Science · 1997 · 1.1K citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death‐dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension

Laimute Taraseviciene‐Stewart, Yasunori Kasahara, Lori Alger et al. · The FASEB Journal · 2001 · 807 citations

Medicine, Pharmacology, Apoptosis +15