John Tayu Lee

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

James Tsai, John Tayu Lee, Weiru Wang et al. · Proceedings of the National Academy of Sciences · 2008 · 1.3K citations · Full text

Acquired Resistance to BRAF Inhibitors Mediated by a RAF Kinase Switch in Melanoma Can Be Overcome by Cotargeting MEK and IGF-1R/PI3K

Jessie Villanueva, Adina Vultur, John Tayu Lee et al. · Cancer Cell · 2010 · 1.2K citations · Full text

Medicine, Receptor Tyrosine Kinase, Melanoma +6

Intercomparison, interpretation, and assessment of spring phenology in North America estimated from remote sensing for 1982–2006

Michael A. White, Kirsten M. de Beurs, Kamel Didan et al. · Global Change Biology · 2009 · 1.1K citations

Climatology, Earth Observation, Phenological Timing +15

Associations between multimorbidity, healthcare utilisation and health status: evidence from 16 European countries

Raffaele Palladino, John Tayu Lee, Mark Ashworth et al. · Age and Ageing · 2016 · 995 citations · Full text

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

James A. McCubrey, Linda S. Steelman, Steven L. Abrams et al. · Advances in Enzyme Regulation · 2006 · 658 citations

Tumor Biology, Health Sciences, Pi3k/pten/akt Pathways +10