Hui San Chin

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

Kate McArthur, Lachlan Whitehead, John M. Heddleston et al. · Science · 2018 · 952 citations

Mitophagy, Apoptosis, Immunology +18

VDAC2 enables BAX to mediate apoptosis and limit tumor development

Hui San Chin, Xiang Li, Iris K. L. Tan et al. · Nature Communications · 2018 · 182 citations · Full text

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

Mark F. van Delft, Stéphane Chappaz, Yelena Khakham et al. · Nature Chemical Biology · 2019 · 50 citations

Knockout Mouse, Apoptosis, Autophagy +8

Sequential genome-wide CRISPR-Cas9 screens identify genes regulating cell-surface expression of tetraspanins

Jicheng Yang, Fusheng Guo, Hui San Chin et al. · Cell Reports · 2023 · 20 citations · Full text

Genetics, Glycobiology, Molecular Biology +23

The <i>BIM</i> deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia

Tun Kiat Ko, Hui San Chin, Charles Chuah et al. · Oncotarget · 2015 · 19 citations · Full text

Mixed-phenotype Acute Leukemia, Genetics, Immunology +19