Concepedia

A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosis

Mark F. van Delft, Stéphane Chappaz, Yelena Khakham, Chinh T. Bui, Marlyse A. Debrincat, Kym N. Lowes, Jason M. Brouwer, Christoph Grohmann, Phillip P. Sharp, Laura F. Dagley,

Nature Chemical Biology · 2019 · 50 citations · 56 references

Concepts

Life SciencesCell BiologyMolecular BiologyApoptosisCell SignalingMolecular Cell BiologyApoptosis ModulationApoptosis RegulationApoptotic Signal TransductionApoptotic SignalingBcl-2 Family ProteinsCell DeathApoptosis Signaling RegulationApoptosis TargetingBcl-2 Protein Binding InteractionsPro-apoptotic Bak ActivationProtein-protein Interactions In Apoptosis

References

56

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

Life Sciences, Bioinformatics, Biology +17

<i>PHENIX</i>: a comprehensive Python-based system for macromolecular structure solution

Paul D. Adams, Pavel V. Afonine, G. Bunkóczi et al. · Acta Crystallographica Section D Biological Crystallography · 2010 · 24.5K citations · Full text

Natural Sciences, Biophysics, Computational Biology +16

<i>Phaser</i>crystallographic software

Airlie J. McCoy, Ralf W. Grosse‐Kunstleve, Paul D. Adams et al. · Journal of Applied Crystallography · 2007 · 20.9K citations · Full text

Natural Sciences, Chemistry, Computational Chemistry +16

Wolfgang Kabsch · Acta Crystallographica Section D Biological Crystallography · 2010 · 16.9K citations · Full text

Computing, Computer Science, Computational Geometry +13

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

Jürgen Cox, Nadin Neuhauser, Annette Michalski et al. · Journal of Proteome Research · 2011 · 5.9K citations · Full text

Life Sciences, Biochemistry, Bioinformatics +17