Concepedia

Jason M. Brouwer

JM

11

Publications

736

Citations

11

H-Index

2011

Active since

Affiliations

Walter and Eliza Hall Institute of Medical Research(Current)

The University of Melbourne

Monash University

La Trobe University

Monash Institute of Medical Research

Jason M. Brouwer is an author at Walter and Eliza Hall Institute of Medical Research specializing in medicine, natural sciences, and biochemistry.

Top concepts

MedicineBiochemistryNatural SciencesApoptosisCell DeathCell BiologyMolecular BiologyCell SignalingStructural BiologyAutophagy

Publications per year

2011–2023

11

Publications

11

Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers

Jason M. Brouwer, Dana Westphal, Grant Dewson et al. · Molecular Cell · 2014 · 156 citations · Full text

Latch Domains Separate, Bak Core

Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy

Jonathan P. Bernardini, Jason M. Brouwer, Iris K. L. Tan et al. · The EMBO Journal · 2018 · 107 citations · Full text

Distinct Mechanisms, Mitophagy, Cell Autophagy +9

Disordered clusters of Bak dimers rupture mitochondria during apoptosis

Rachel T. Uren, Martin O’Hely, Sweta Iyer et al. · eLife · 2017 · 97 citations · Full text

Proteinlipid Interaction, Apoptosis, Molecular Biology +16

Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax

Colin Hockings, Khatira Anwari, Robert L. Ninnis et al. · Cell Death and Disease · 2015 · 94 citations · Full text

BAK core dimers bind lipids and can be bridged by them

Angus D. Cowan, Nicholas A. Smith, Jarrod J. Sandow et al. · Nature Structural & Molecular Biology · 2020 · 66 citations

Proteinlipid Interaction, Biochemistry, Bak Core Dimers +6

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