Jonathan P. Bernardini

Mechanism and inhibition of the papain‐like protease, PLpro, of SARS‐CoV‐2

Theresa Klemm, Gregor Ebert, Dale J. Calleja et al. · The EMBO Journal · 2020 · 478 citations · Full text

Protein Function, Biochemistry, Natural Sciences +3

Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagy

Jonathan P. Bernardini, Jason M. Brouwer, Iris K. L. Tan et al. · The EMBO Journal · 2018 · 107 citations · Full text

Distinct Mechanisms, Mitophagy, Cell Autophagy +9

Distinct Features of Stress Granule Proteins Predict Localization in Membraneless Organelles

Erich R. Kuechler, Paulina Budzyńska, Jonathan P. Bernardini et al. · Journal of Molecular Biology · 2020 · 76 citations · Full text

Molecular Biology, Membraneless Organelles, Protein Phase Separation +19

BAK core dimers bind lipids and can be bridged by them

Angus D. Cowan, Nicholas A. Smith, Jarrod J. Sandow et al. · Nature Structural & Molecular Biology · 2020 · 66 citations

Proteinlipid Interaction, Biochemistry, Bak Core Dimers +6

Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design

Jason M. Brouwer, Ping Lan, Angus D. Cowan et al. · Molecular Cell · 2017 · 65 citations · Full text

Biochemistry, Medicine, Structure-based Design +3