Xiang Li

Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer

Delphine Mérino, James R. Whittle, François Vaillant et al. · Science Translational Medicine · 2017 · 190 citations

Breast Oncology, Bh3 Mimetics, Medicine +13

VDAC2 enables BAX to mediate apoptosis and limit tumor development

Hui San Chin, Xiang Li, Iris K. L. Tan et al. · Nature Communications · 2018 · 182 citations · Full text

High-fat diet impairs gut barrier through intestinal microbiota-derived reactive oxygen species

Nianyi Zeng, Fan Wu, Jun-Qi Lu et al. · Science China Life Sciences · 2023 · 54 citations

Nutrition, High-fat Diet Impairs, Dysbiosis +11

BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association

Michael A. Dengler, A.Y. Robin, Leonie Gibson et al. · Cell Reports · 2019 · 52 citations · Full text

Mom Association, Mitochondrial Function, Mitochondrial Dynamic +14

BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove

Xiang Li, Iris K. L. Tan, Colin Hockings et al. · Proceedings of the National Academy of Sciences · 2017 · 40 citations · Full text