Lachlan Whitehead

BAK/BAX macropores facilitate mitochondrial herniation and mtDNA efflux during apoptosis

Kate McArthur, Lachlan Whitehead, John M. Heddleston et al. · Science · 2018 · 952 citations

Mitophagy, Apoptosis, Immunology +18

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

Stephanie A. Conos, Kaiwen Chen, Dominic De Nardo et al. · Proceedings of the National Academy of Sciences · 2017 · 466 citations · Full text

Apoptosis, Immunology, Immune Regulation +26

MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis

André L. Samson, Ying Zhang, Niall D. Geoghegan et al. · Nature Communications · 2020 · 335 citations · Full text

RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers

Emma Nolan, François Vaillant, Daniel Branstetter et al. · Nature Medicine · 2016 · 301 citations

Breast Oncology, Oncology, Brca1-mutation Carriers +11

Essential Role of the PfRh5/PfRipr/CyRPA Complex during Plasmodium falciparum Invasion of Erythrocytes

Jennifer Volz, Alan Yap, Xavier Sisquella et al. · Cell Host & Microbe · 2016 · 224 citations · Full text

Signal Transduction, Essential Role, Biochemistry +11