Prasanth R. Nyalapatla

Ligand-induced Dimerization of Middle East Respiratory Syndrome (MERS) Coronavirus nsp5 Protease (3CLpro)

Sakshi Tomar, Melanie L. Johnston, Sarah E. St. John et al. · Journal of Biological Chemistry · 2015 · 171 citations · Full text

Protease Inhibitors, Virus Structure, Coronavirus Nsp5 Protease +8

Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity

Haydar Bulut, Shin‐ichiro Hattori, Hiromi Aoki-Ogata et al. · Scientific Reports · 2020 · 81 citations · Full text

Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants

Arun K. Ghosh, Kalapala Venkateswara Rao, Prasanth R. Nyalapatla et al. · Journal of Medicinal Chemistry · 2017 · 73 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Hiv-1 Protease +15

A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency

Manabu Aoki, Hironori Hayashi, Kalapala Venkateswara Rao et al. · eLife · 2017 · 51 citations · Full text

Zinc Catalyzed and Mediated Asymmetric Propargylation of Trifluoromethyl Ketones with a Propargyl Boronate

Daniel R. Fandrick, Jonathan T. Reeves, Johanna M. Bakonyi et al. · The Journal of Organic Chemistry · 2013 · 50 citations