Kalapala Venkateswara Rao

Severe Acute Respiratory Syndrome Coronavirus Papain-like Novel Protease Inhibitors: Design, Synthesis, Protein−Ligand X-ray Structure and Biological Evaluation

Arun K. Ghosh, Jun Takayama, Kalapala Venkateswara Rao et al. · Journal of Medicinal Chemistry · 2010 · 157 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Butyrolactones from Aspergillus terreus.

Kalapala Venkateswara Rao, Anup Kumar Sadhukhan, M. Veerender et al. · Chemical and Pharmaceutical Bulletin · 2000 · 121 citations · Full text

Life Sciences, Chemistry, Microbiology +15

Single atom changes in newly synthesized HIV protease inhibitors reveal structural basis for extreme affinity, high genetic barrier, and adaptation to the HIV protease plasticity

Haydar Bulut, Shin‐ichiro Hattori, Hiromi Aoki-Ogata et al. · Scientific Reports · 2020 · 82 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +16

Design and Development of Highly Potent HIV-1 Protease Inhibitors with a Crown-Like Oxotricyclic Core as the P2-Ligand To Combat Multidrug-Resistant HIV Variants

Arun K. Ghosh, Kalapala Venkateswara Rao, Prasanth R. Nyalapatla et al. · Journal of Medicinal Chemistry · 2017 · 73 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

A novel central nervous system-penetrating protease inhibitor overcomes human immunodeficiency virus 1 resistance with unprecedented aM to pM potency

Manabu Aoki, Hironori Hayashi, Kalapala Venkateswara Rao et al. · eLife · 2017 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17