Hwa-Kwo Yen

Structure-activity studies of rapamycin analogs: evidence that the C-7 methoxy group is part of the effector domain and positioned at the FKBP12-FRAP interface

Juan I. Luengo, Dennis S. Yamashita, Damien J. Dunnington et al. · Chemistry & Biology · 1995 · 41 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +11

(6,7-Dimethoxy-2,4-dihydroindeno[1,2-<i>c</i>]pyrazol-3-yl)phenylamines:  Platelet-Derived Growth Factor Receptor Tyrosine Kinase Inhibitors with Broad Antiproliferative Activity against Tumor Cells

Chih Y. Ho, Donald Ludovici, Umar S. M. Maharoof et al. · Journal of Medicinal Chemistry · 2005 · 34 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Structure-activity studies of synthetic FKBP ligands as peptidyl-prolyl isomerase inhibitors

Dennis A. Holt, Arda Konialian-Beck, Hye-Ja Oh et al. · Bioorganic & Medicinal Chemistry Letters · 1994 · 33 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

3-Phosphinic acid and 3-phosphonic acid steroids as inhibitors of steroid 5α-reductase: Species comparison and mechanistic studies

Mark A. Levy, Brian W. Metcalf, Martín Brandt et al. · Bioorganic Chemistry · 1991 · 20 citations

Life Sciences, Biochemistry, Medicinal Chemistry +14

Inhibition of steroid 5α-reductase by 3-nitrosteroids: synthesis, mechanism of inhibition, and in vivo activity.

Dennis A. Holt, Mark A. Levy, Hwa-Kwo Yen et al. · Bioorganic & Medicinal Chemistry Letters · 1991 · 20 citations

Life Sciences, Biochemistry, Pharmacology +11