Martín Brandt

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

Michael T. McCabe, Heidi M. Ott, Gopinath Ganji et al. · Nature · 2012 · 1.8K citations

Ezh2 Inhibition, Lymphoid Neoplasia, Hematological Malignancy +10

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

Michael T. McCabe, Alan P. Graves, Gopinath Ganji et al. · Proceedings of the National Academy of Sciences · 2012 · 481 citations · Full text

Histone Modifications, Epigenetic Change, Pathology +20

Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction

Aidan G. Gilmartin, Thomas Faitg, Mark C. Richter et al. · Nature Chemical Biology · 2014 · 204 citations

Proteinlipid Interaction, Protein Function, Signal Transduction +8

Assay of short-chain acyl coenzyme a intermediates in tissue extracts by high-pressure liquid chromatography

Barbara E. Corkey, Martín Brandt, Rebecca J. Williams et al. · Analytical Biochemistry · 1981 · 129 citations

Biochemistry, Medicine, Bioanalysis +7

Inhibition of steroid 5.alpha.-reductase by unsaturated 3-carboxy steroids

Dennis A. Holt, Mark A. Levy, Hye Ja Oh et al. · Journal of Medicinal Chemistry · 1990 · 99 citations · Full text

Medicinal Chemistry, Enantioselective Synthesis, Human Enzyme +12