Mark C. Richter

Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction

Aidan G. Gilmartin, Thomas Faitg, Mark C. Richter et al. · Nature Chemical Biology · 2014 · 208 citations

Life Sciences, Biochemistry, Molecular Biology +14

Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate)

Hiroyuki Abé, Shinichi Kikuchi, Kazuhide Hayakawa et al. · ACS Medicinal Chemistry Letters · 2011 · 193 citations

Medicine, Oncology, Pharmacology +13

Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis

Aidan G. Gilmartin, Maureen R. Bleam, Mark C. Richter et al. · Cancer Research · 2009 · 133 citations · Full text

Life Sciences, Pharmacology, Apoptosis +13

Sensitivity of Cancer Cells to Plk1 Inhibitor GSK461364A Is Associated with Loss of p53 Function and Chromosome Instability

Yan Degenhardt, Joel Greshock, Sylvie Laquerre et al. · Molecular Cancer Therapeutics · 2010 · 91 citations

Life Sciences, Molecular Biology, Oncology +17

WIP1 Phosphatase as a Potential Therapeutic Target in Neuroblastoma

Mark C. Richter, Tajhal Dayaram, Aidan G. Gilmartin et al. · PLoS ONE · 2015 · 67 citations · Full text

Life Sciences, Molecular Biology, Oncology +17