Hye-Ja Oh

A highly potent inhibitor of cathepsin K (relacatib) reduces biomarkers of bone resorption both in vitro and in an acute model of elevated bone turnover in vivo in monkeys

Sanjay Kumar, Lauren Dare, Janice A. Vasko-Moser et al. · Bone · 2006 · 136 citations

Animal Physiology, Sclerostin, Bone Resorption +12

Orally Active and Potent Inhibitors of γ-Aminobutyric Acid Uptake

Fadia E. Ali, William E. Bondinell, Penelope A. Dandridge et al. · Journal of Medicinal Chemistry · 1985 · 130 citations · Full text

Pharmacotherapy, Experimental Pharmacology, Molecular Pharmacology +16

Structure and Design of Potent and Selective Cathepsin K Inhibitors

Dennis S. Yamashita, Ward W. Smith, Baoguang Zhao et al. · Journal of the American Chemical Society · 1997 · 106 citations

Molecular Recognition, Molecular Pharmacology, Medicinal Chemistry +14

Azepanone-Based Inhibitors of Human and Rat Cathepsin K

Robert W. Marquis, Yu Ru, Steven M. LoCastro et al. · Journal of Medicinal Chemistry · 2001 · 102 citations · Full text

Use of Papain as a Model for the Structure-Based Design of Cathepsin K Inhibitors:  Crystal Structures of Two Papain−Inhibitor Complexes Demonstrate Binding to S‘-Subsites

Judith M. LaLonde, Baoguang Zhao, Ward W. Smith et al. · Journal of Medicinal Chemistry · 1998 · 77 citations · Full text

Bioorganic Chemistry, Bone Resorption, Aldo-keto Reductase +21