Robert W. Marquis

Toll-like Receptor 3-mediated Necrosis via TRIF, RIP3, and MLKL

William J. Kaiser, Haripriya Sridharan, Chunzi Huang et al. · Journal of Biological Chemistry · 2013 · 941 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang et al. · Nature · 2018 · 865 citations

Medicine, Medicinal Chemistry, Pharmacology +10

MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates

Yves Dondelinger, Wim Declercq, Sylvie Montessuit et al. · Cell Reports · 2014 · 818 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

Pratyusha Mandal, Scott B. Berger, Sirika Pillay et al. · Molecular Cell · 2014 · 615 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

Philip A. Harris, Scott B. Berger, Jae Uk Jeong et al. · Journal of Medicinal Chemistry · 2017 · 475 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15