Concepedia

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang, N.O. Concha, Robert R. Singhaus, Shuyun Zhang, Jean-Luc Tran, Patrick Moore, Stephanie Lehmann, H. Christian Eberl,

Nature · 2018 · 865 citations · 21 references

DOI

Concepts

References

21

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

, , +12

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

Hiroki Ishikawa, Zhe Ma, Glen N. Barber · Nature · 2009 · 2.7K citations · Full text

, , +14

STING-Dependent Cytosolic DNA Sensing Mediates Innate Immune Recognition of Immunogenic Tumors

Seng‐Ryong Woo, Mercedes B. Fuertes, Leticia Corrales et al. · Immunity · 2014 · 1.8K citations · Full text

, , +12

Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity

Leticia Corrales, Laura Hix Glickman, Sarah M. McWhirter et al. · Cell Reports · 2015 · 1.5K citations · Full text

, , +17

Activated STING in a Vascular and Pulmonary Syndrome

Adriana A. de Jesus, Bernadette Marrero, Dan Yang et al. · New England Journal of Medicine · 2014 · 1.4K citations · Full text

, , +14