N.O. Concha

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang et al. · Nature · 2018 · 803 citations

Systemic Activity, Medicine, Mechanism Of Action +4

A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC

Helai P. Mohammad, Kimberly N. Smitheman, Chandrashekhar D. Kamat et al. · Cancer Cell · 2015 · 498 citations · Full text

Oncogenic Agent, Medicine, Epigenetic Change +9

Crystal structure of the wide-spectrum binuclear zinc β-lactamase from Bacteroides fragilis

N.O. Concha, Beth A. Rasmussen, Karen Bush et al. · Structure · 1996 · 358 citations · Full text

Crystal Structure, Biochemistry, Bacteriology +7

Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss

Andrew Fedoriw, Satyajit Rajapurkar, Shane W. O’Brien et al. · Cancer Cell · 2019 · 333 citations · Full text

Cancer Research, Mtap Loss, Medicine +10

Ca2+-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V

Manal A. Swairjo, N.O. Concha, Marcia A. Kaetzel et al. · Nature Structural & Molecular Biology · 1995 · 311 citations

Proteinlipid Interaction, Protein Function, Signal Transduction +7