N.O. Concha

Design of amidobenzimidazole STING receptor agonists with systemic activity

Joshi M. Ramanjulu, G. Scott Pesiridis, Jingsong Yang et al. · Nature · 2018 · 865 citations

Medicine, Medicinal Chemistry, Pharmacology +10

A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC

Helai P. Mohammad, Kimberly N. Smitheman, Chandrashekhar D. Kamat et al. · Cancer Cell · 2015 · 512 citations · Full text

Medicine, Molecular Biology, Oncology +12

Crystal structure of the wide-spectrum binuclear zinc β-lactamase from Bacteroides fragilis

N.O. Concha, Beth A. Rasmussen, Karen Bush et al. · Structure · 1996 · 358 citations · Full text

Natural Sciences, Biochemistry, Microbiology +14

Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss

Andrew Fedoriw, Satyajit Rajapurkar, Shane W. O’Brien et al. · Cancer Cell · 2019 · 347 citations · Full text

Medicine, Oncology, Pharmacology +7

Ca2+-bridging mechanism and phospholipid head group recognition in the membrane-binding protein annexin V

Manal A. Swairjo, N.O. Concha, Marcia A. Kaetzel et al. · Nature Structural & Molecular Biology · 1995 · 313 citations

Life Sciences, Biochemistry, Biophysics +13