Helai P. Mohammad

A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing

Joyce E. Ohm, Kelly M. McGarvey, Xiaobing Yu et al. · Nature Genetics · 2007 · 1.1K citations · Full text

Chromatin, Heritable Silencing, Chromatin Structure +14

A DNA Hypomethylation Signature Predicts Antitumor Activity of LSD1 Inhibitors in SCLC

Helai P. Mohammad, Kimberly N. Smitheman, Chandrashekhar D. Kamat et al. · Cancer Cell · 2015 · 498 citations · Full text

Oncogenic Agent, Medicine, Epigenetic Change +9

Alterations of immune response of non-small cell lung cancer with Azacytidine

John Wrangle, Wei Wang, Alexander Koch et al. · Oncotarget · 2013 · 382 citations · Full text

Double Strand Breaks Can Initiate Gene Silencing and SIRT1-Dependent Onset of DNA Methylation in an Exogenous Promoter CpG Island

Heather M. O’Hagan, Helai P. Mohammad, Stephen B. Baylin · PLoS Genetics · 2008 · 379 citations · Full text

Histone Modifications, Sirt1-dependent Onset, Dna Base Oxidation +21

Anti-tumor Activity of the Type I PRMT Inhibitor, GSK3368715, Synergizes with PRMT5 Inhibition through MTAP Loss

Andrew Fedoriw, Satyajit Rajapurkar, Shane W. O’Brien et al. · Cancer Cell · 2019 · 333 citations · Full text

Cancer Research, Mtap Loss, Medicine +10