Karen Bush

Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of<i>Klebsiella pneumoniae</i>

Hesna Yigit, Anne Marie Queenan, Gregory J. Anderson et al. · Antimicrobial Agents and Chemotherapy · 2001 · 1.6K citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase

Ari Robicsek, Jacob Strahilevitz, George A. Jacoby et al. · Nature Medicine · 2005 · 1K citations

Life Sciences, Biochemistry, Pharmacology +14

Imipenem resistance in Klebsiella pneumoniae is associated with the combination of ACT-1, a plasmid-mediated AmpC beta-lactamase, and the foss of an outer membrane protein

Patricia A. Bradford, Carl Urban, N Mariano et al. · Antimicrobial Agents and Chemotherapy · 1997 · 451 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +15

Crystal structure of the wide-spectrum binuclear zinc β-lactamase from Bacteroides fragilis

N.O. Concha, Beth A. Rasmussen, Karen Bush et al. · Structure · 1996 · 358 citations · Full text

Natural Sciences, Biochemistry, Microbiology +14

Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria

R. B. Sykes, D P Bonner, Karen Bush et al. · Antimicrobial Agents and Chemotherapy · 1982 · 311 citations

Life Sciences, Microbiology, Pharmacology +12