RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

Pratyusha Mandal, Scott B. Berger, Sirika Pillay, +27

Molecular Cell

Cell RegulationPronecrotic Kinase ActivityReceptor Tyrosine KinaseApoptosisAutophagy +4

Parallel shRNA and CRISPR-Cas9 screens enable antiviral drug target identification

Richard M. Deans, David W. Morgens, Ayşe Ökesli, +11

Nature Chemical Biology

Off-target EffectEngineeringParallel ShrnaImmunologyGenetic Engineering +8

Adeno-associated Virus (AAV) Serotypes Have Distinctive Interactions with Domains of the Cellular AAV Receptor

Sirika Pillay, Wei Zou, Fang Cheng, +12

Journal of Virology

GPR108 Is a Highly Conserved AAV Entry Factor

Amanda M. Dudek, Nerea Zabaleta, Eric Zinn, +8

Molecular Therapy

An Alternate Route for Adeno-associated Virus (AAV) Entry Independent of AAV Receptor

Amanda M. Dudek, Sirika Pillay, Andreas S. Puschnik, +5

Journal of Virology

Cell-Selective Adeno-Associated Virus-Mediated <i>SCN1A</i> Gene Regulation Therapy Rescues Mortality and Seizure Phenotypes in a Dravet Syndrome Mouse Model and Is Well Tolerated in Nonhuman Primates

Annie Tanenhaus, T. D. Stowe, Andrew L. Young, +14

Human Gene Therapy

Optimization of chimeric HIV‐1 virus‐like particle production in a baculovirus‐insect cell expression system

Sirika Pillay, Ann E. Meyers, Anna‐Lise Williamson, +1

Biotechnology Progress

Viral ReplicationEngineeringImmunologyInsect CellsHuman Retrovirus +14

Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression

James Zengel, Yu Xin Wang, Jai Woong Seo, +17

Nature Methods

Chimaeric HIV-1 subtype C Gag molecules with large in-frame C-terminal polypeptide fusions form virus-like particles

Richard James Halsey, Fiona L. Tanzer, Ann E. Meyers, +5

Virus Research

Virus StructureViral ReplicationHuman RetrovirusImmunologyAntiviral Response +6

HIV-1 sub-type C chimaeric VLPs boost cellular immune responses in mice

Sirika Pillay, Enid Shephard, Ann E. Meyers, +2

Journal of Immune Based Therapies and Vaccines