Concepedia

Yu Ru

YR

Statistics

Publications

13

Citations

1.6K

H-Index

13

Active since

1994

Affiliations

New Frontier(Current)

Institute of Biophysics

Dezhou University

Sun Yat-sen University

GlaxoSmithKline (United States)

Yu Ru is an author at New Frontier specializing in pharmacology, enzyme inhibition, and cathepsin activity.

ORCID

Publications per year

1994–2023

13

Publications

13

Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors

Patrick Y. S. Lam, Prabhakar K. Jadhav, Charles J. Eyermann et al. · Science · 1994 · 836 citations

, , +16

Cyclic HIV Protease Inhibitors:  Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas

Patrick Y. S. Lam, Yu Ru, Prabhakar K. Jadhav et al. · Journal of Medicinal Chemistry · 1996 · 170 citations · Full text

, , +17

Potent and Selective Inhibition of Human Cathepsin K Leads to Inhibition of Bone Resorption In Vivo in a Nonhuman Primate

George B. Stroup, Michael W. Lark, Daniel F. Veber et al. · Journal of Bone and Mineral Research · 2001 · 153 citations

, , +17

Azepanone-Based Inhibitors of Human and Rat Cathepsin K

Robert W. Marquis, Yu Ru, Steven M. LoCastro et al. · Journal of Medicinal Chemistry · 2001 · 102 citations · Full text

, , +15

A potent small molecule, nonpeptide inhibitor of cathepsin K (SB 331750) prevents bone matrix resorption in the ovariectomized rat

Michael W. Lark, George B. Stroup, Ian E. James et al. · Bone · 2002 · 78 citations

, , +10

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