Michael W. Lark

Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques.

Zorina S. Galis, Galina K. Sukhova, Michael W. Lark et al. · Journal of Clinical Investigation · 1994 · 2.5K citations · Full text

Veterinary Medicine, Cardiology, Pathology +16

A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine

Scott M. DeWire, Dennis S. Yamashita, David H. Rominger et al. · Journal of Pharmacology and Experimental Therapeutics · 2013 · 655 citations

Medicine, Medicinal Chemistry, Pharmacology +17

Cytokine-stimulated human vascular smooth muscle cells synthesize a complement of enzymes required for extracellular matrix digestion.

Zorina S. Galis, Maria Muszynski, Galina K. Sukhova et al. · Circulation Research · 1994 · 645 citations

Life Sciences, Cell Biology, Pathology +16

Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints.

Michael W. Lark, E K Bayne, J. Flanagan et al. · Journal of Clinical Investigation · 1997 · 472 citations · Full text

Medicine, Orthopaedic Surgery, Pathology +17

Discoordinate expression of stromelysin, collagenase, and tissue inhibitor of metalloproteinases-1 in rheumatoid human synovial fibroblasts. Synergistic effects of interleukin-1 and tumor necrosis factor-alpha on stromelysin expression.

Karen L. MacNaul, Nicole Chartrain, Michael W. Lark et al. · Journal of Biological Chemistry · 1990 · 404 citations · Full text

Medicine, Immunology, Pathology +16