Scott M. DeWire

A G Protein-Biased Ligand at the μ-Opioid Receptor Is Potently Analgesic with Reduced Gastrointestinal and Respiratory Dysfunction Compared with Morphine

Scott M. DeWire, Dennis S. Yamashita, David H. Rominger et al. · Journal of Pharmacology and Experimental Therapeutics · 2013 · 655 citations

Medicine, Medicinal Chemistry, Pharmacology +17

A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling

James W. Wisler, Scott M. DeWire, Erin J. Whalen et al. · Proceedings of the National Academy of Sciences · 2007 · 598 citations · Full text

Medicine, Cardiology, Pharmacology +17

Quantifying Ligand Bias at Seven-Transmembrane Receptors

Sudarshan Rajagopal, Seungkirl Ahn, David H. Rominger et al. · Molecular Pharmacology · 2011 · 390 citations

Medicine, Molecular Biology, Pharmacology +17

Selectively Engaging β-Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance

Jonathan D. Violin, Scott M. DeWire, Dennis S. Yamashita et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 370 citations

Medicine, Cardiology, Pharmacology +17

β-Arrestin1 mediates nicotinic acid–induced flushing, but not its antilipolytic effect, in mice

Robert W. Walters, Arun K. Shukla, Jeffrey J. Kovacs et al. · Journal of Clinical Investigation · 2009 · 233 citations · Full text

Life Sciences, Biochemistry, Pharmacology +15