David J. Calderwood

Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I

Lee D. Arnold, David J. Calderwood, R. W. Dixon et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 93 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +8

Discovery and Characterization of Non-ATP Site Inhibitors of the Mitogen Activated Protein (MAP) Kinases

Kenneth M. Comess, Chaohong Sun, Cele Abad‐Zapatero et al. · ACS Chemical Biology · 2010 · 80 citations

Drug Target, Kinase Inhibitors, Molecular Biology +22

Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck — a selectivity insight

Andrew Burchat, David J. Calderwood, Michael Friedman et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 76 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +12

Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection

Andrew Burchat, David W. Borhani, David J. Calderwood et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 75 citations · Full text

Transplantation, Organ Allograft Rejection, Medicine +9

A-770041, a Novel and Selective Small-Molecule Inhibitor of Lck, Prevents Heart Allograft Rejection

Robert F. Stachlewitz, Michelle Hart, Brian R. Bettencourt et al. · Journal of Pharmacology and Experimental Therapeutics · 2005 · 56 citations