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Pyrrolo[2,3-d]pyrimidines containing an extended 5-substituent as potent and selective inhibitors of lck I

Lee D. Arnold, David J. Calderwood, R. W. Dixon, David N. Johnston, Joanne Kamens, Rainer Munschauer, Paul Rafferty, S Ratnofsky

Bioorganic & Medicinal Chemistry Letters · 2000 · 93 citations · 9 references

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9

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor

Jeffrey H. Hanke, Joseph P. Gardner, Robert L. Dow et al. · Journal of Biological Chemistry · 1996 · 2K citations · Full text

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Three-dimensional structure of the tyrosine kinase c-Src

Wenqing Xu, Stephen C. Harrison, Michael J. Eck · Nature · 1997 · 1.4K citations

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Crystal structure of the Src family tyrosine kinase Hck

Frank Sicheri, Ismail Moarefi, John Kuriyan · Nature · 1997 · 1.2K citations

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Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

Hiroto Yamaguchi, Wayne A. Hendrickson · Nature · 1996 · 491 citations

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Crystal Structure of Hck in Complex with a Src Family–Selective Tyrosine Kinase Inhibitor

Thomas H. Schindler, Frank Sicheri, Alexander R. Pico et al. · Molecular Cell · 1999 · 426 citations · Full text

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