Lee D. Arnold

Inhibition of Epidermal Growth Factor Receptor-Associated Tyrosine Phosphorylation in Human Carcinomas with CP-358,774: Dynamics of Receptor Inhibition In Situ and Antitumor Effects in Athymic Mice

Vincent A. Pollack, Douglas M. Savage, Deborah A. Baker et al. · Journal of Pharmacology and Experimental Therapeutics · 1999 · 430 citations

Discovery of OSI-906: A Selective and Orally Efficacious Dual Inhibitor of the IGF-1 Receptor and Insulin Receptor

Mark J. Mulvihill, Andrew Cooke, Maryland Rosenfeld-Franklin et al. · Future Medicinal Chemistry · 2009 · 307 citations · Full text

Preclinical Characterization of OSI-027, a Potent and Selective Inhibitor of mTORC1 and mTORC2: Distinct from Rapamycin

Shripad V. Bhagwat, Prafulla C. Gokhale, Andrew P. Crew et al. · Molecular Cancer Therapeutics · 2011 · 200 citations

Conversion of serine to stereochemically pure .beta.-substituted .alpha.-amino acids via .beta.-lactones

Lee D. Arnold, Thomas H. Kalantar, John C. Vederas · Journal of the American Chemical Society · 1985 · 180 citations

Biosynthesis, Bioorganic Chemistry, Engineering +12

Thienopyrimidine Ureas as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors

Yujia Dai, Yan Guo, Robin R. Frey et al. · Journal of Medicinal Chemistry · 2005 · 152 citations · Full text

Drug Target, Pharmacotherapy, Pharmaceutical Chemistry +17