Future Medicinal Chemistry

Marine Natural Products: A New Wave of Drugs?

Rana Montaser, Hendrik Luesch · 2011 · 425 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Strategies for Discovering and Derisking Covalent, Irreversible Enzyme Inhibitors

Douglas S. Johnson, Eranthie Weerapana, Benjamin F. Cravatt · 2010 · 389 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Fluorine in Medicinal Chemistry: A Century of Progress and a 60-Year Retrospective of Selected Highlights

Robert Filler, Rituparna Saha · 2009 · 336 citations

Medicine, Medicinal Chemistry, Nuclear Medicine +12

Discovery of OSI-906: A Selective and Orally Efficacious Dual Inhibitor of the IGF-1 Receptor and Insulin Receptor

Mark J. Mulvihill, Andrew Cooke, Maryland Rosenfeld-Franklin et al. · 2009 · 308 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +15

Conformational Adaptation in Drug–Target Interactions and Residence Time

Robert A. Copeland · 2011 · 199 citations

Pharmacy, Pharmacokinetics, Pharmacology +17