Douglas S. Johnson

Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

Kay Ahn, Douglas S. Johnson, Mauro Mileni et al. · Chemistry & Biology · 2009 · 439 citations · Full text

Inflammation, Anti-inflammatory, Health Sciences +13

Strategies for Discovering and Derisking Covalent, Irreversible Enzyme Inhibitors

Douglas S. Johnson, Eranthie Weerapana, Benjamin F. Cravatt · Future Medicinal Chemistry · 2010 · 383 citations · Full text

Medicinal Chemistry, Covalent Inhibitors, Covalent Inhibitor +13

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Ji‐Yeun Hur, Georgia Frost, Xianzhong Wu et al. · Nature · 2020 · 360 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +8

CC‐1065 and the Duocarmycins: Understanding their Biological Function through Mechanistic Studies

Dale L. Boger, Douglas S. Johnson · Angewandte Chemie International Edition in English · 1996 · 318 citations

Mechanistic Studies, Gastrointestinal Pharmacology, Molecular Biology +21

Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain

Kay Ahn, Sarah E. Smith, Marya Liimatta et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 228 citations · Full text