The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Ji‐Yeun Hur, Georgia Frost, Xianzhong Wu, +28

Nature

Neurodegenerative DiseasesAlzheimer's DiseaseMedicineImmune RegulationImmunology +6

Intraperitoneal injection of the pancreatic peptide amylin potently reduces behavioral impairment and brain amyloid pathology in murine models of Alzheimer’s disease

Haihao Zhu, X Wang, Max Wallack, +12

Molecular Psychiatry

Active γ‐secretase is localized to detergent‐resistant membranes in human brain

Ji‐Yeun Hur, Hedvig Welander, Homira Behbahani, +5

FEBS Journal

Proteinlipid InteractionProtein SecretionLipid MovementAmyloid Precursor ProteinSocial Sciences +18

Synaptic and Endosomal Localization of Active γ-Secretase in Rat Brain

Susanne Frykman, Ji‐Yeun Hur, Jenny Frånberg, +5

PLoS ONE

Identification of Novel γ-Secretase-associated Proteins in Detergent-resistant Membranes from Brain

Ji‐Yeun Hur, Yasuhiro Teranishi, Takahiro Kihara, +7

Journal of Biological Chemistry

Modeling Alzheimer’s Disease in Mouse without Mutant Protein Overexpression: Cooperative and Independent Effects of Aβ and Tau

Qinxi Guo, Hongmei Li, Allysa Cole, +3

PLoS ONE

Affinity pulldown of γ‐secretase and associated proteins from human and rat brain

Yasuhiro Teranishi, Ji‐Yeun Hur, Hedvig Welander, +5

Journal of Cellular and Molecular Medicine

Protein Secretionγ-Secretase ComponentsAssociated ProteinsMolecular BiologyAffinity Pulldown +21

Identification of two novel synaptic γ-secretase associated proteins that affect amyloid β-peptide levels without altering Notch processing

Susanne Frykman, Yasuhiro Teranishi, Ji‐Yeun Hur, +9

Neurochemistry International

Notch ProcessingNeurodegenerative DiseasesProtein FunctionMolecular NeuroscienceNovel Synaptic γ-Secretase +9

Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production

Yasuhiro Teranishi, Ji‐Yeun Hur, Gucci Jijuan Gu, +8

Biochemical and Biophysical Research Communications

Neurodegenerative DiseasesProtein SecretionAlzheimer's DiseaseMolecular NeuroscienceSignal Transduction +9

P2‐279: Affinity pulldown of gamma‐secretase and associated proteins from human and rat brain

Yasuhiro Teranishi, Ji‐Yeun Hur, Hedvig Welander, +5

Alzheimer s & Dementia

Protein SecretionAssociated ProteinsMolecular BiologyPeptide ScienceAmyloid Precursor Protein +17