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Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain

Kay Ahn, Sarah E. Smith, Marya Liimatta, David Beidler, Nalini Sadagopan, David T. Dudley, Tim Young, Paul Wren, Yanhua Zhang, Steven Swaney,

Journal of Pharmacology and Experimental Therapeutics · 2011 · 231 citations · 38 references

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38

Efficient Analysis of Experimental Observations

W. J. Dixon · The Annual Review of Pharmacology and Toxicology · 1980 · 2.2K citations

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Molecular characterization of an enzyme that degrades neuromodulatory fatty-acid amides

Benjamin F. Cravatt, Dan K. Giang, Stephen P. Mayfield et al. · Nature · 1996 · 2.1K citations

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Supersensitivity to anandamide and enhanced endogenous cannabinoid signaling in mice lacking fatty acid amide hydrolase

Benjamin F. Cravatt, Kristin Demarest, Matthew P. Patricelli et al. · Proceedings of the National Academy of Sciences · 2001 · 1.3K citations · Full text

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Modulation of anxiety through blockade of anandamide hydrolysis

Satish Kathuria, Silvana Gaetani, Darren Fegley et al. · Nature Medicine · 2002 · 1.3K citations · Full text

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Activity-Based Protein Profiling in Vivo Using a Copper(I)-Catalyzed Azide-Alkyne [3 + 2] Cycloaddition

Anna E Speers, Gregory C. Adam, Benjamin F. Cravatt · Journal of the American Chemical Society · 2003 · 948 citations

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