Concepedia

Endocannabinoid System

The Endocannabinoid System is a neuromodulatory biological system composed of endogenous lipid-based neurotransmitters, their synthesizing and degrading enzymes, and specific G protein-coupled receptors that together regulate synaptic transmission and maintain physiological homeostasis.

4.2K

Publications

316.8K

Citations

15.8K

Authors

2.7K

Institutions

Publications per year

2017–2026

1.3K

Variants

Ecs

Parents

Publications

4.2K

Molecular characterization of a peripheral receptor for cannabinoids

Sean Munro, Kerrie L. Thomas, Muna Abu-Shaar · Nature · 1993 · 5.1K citations

, , +14

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

Lisa A. Matsuda, Stephen J. Lolait, Michael Brownstein et al. · Nature · 1990 · 5K citations

, , +11

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

Raphael Mechoulam, Shimon Ben‐Shabat, L Hanŭs et al. · Biochemical Pharmacology · 1995 · 2.9K citations

, , +10

2-Arachidonoylgylcerol: A Possible Endogenous Cannabinoid Receptor Ligand in Brain

Takayuki Sugiura, Shigeru Kondo, Akihiro Sukagawa et al. · Biochemical and Biophysical Research Communications · 1995 · 2.2K citations

, , +9

The endogenous cannabinoid system controls extinction of aversive memories

Giovanni Marsicano, Carsten T. Wotjak, Shahnaz Christina Azad et al. · Nature · 2002 · 1.7K citations

, , +14

1–5 of 4.2K

Authors

15.8K

  1. VD
    Vincenzo Di Marzo

    National Research Council, Italy

    279 publications · 37.3K citations

    103

    h-index

  2. BF
    Benjamin F. Cravatt

    Scripps Research Institute, United States

    115 publications · 14.7K citations

    70

    h-index

  3. KM
    Ken Mackie

    Indiana University Bloomington, United States

    111 publications · 15.5K citations

    65

    h-index

  4. MM
    Mauro Maccarrone

    University of Teramo, Italy

    141 publications · 10K citations

    59

    h-index

  5. DP
    Daniele Piomelli

    University of California, Irvine, United States

    89 publications · 17.3K citations

    56

    h-index

1–5 of 15.8K

Institutions

2.7K

  1. Scripps Research Institute

    San Diego, United States

    76 h-index

    442 publications

    56.9K citations

  2. National Institute on Alcohol Abuse and Alcoholism

    Bethesda, United States

    68 h-index

    384 publications

    78.3K citations

  3. National Institutes of Health

    Bethesda, United States

    66 h-index

    399 publications

    74.8K citations

  4. Inserm

    Paris, France

    64 h-index

    567 publications

    74.3K citations

  5. National Research Council

    Rome, Italy

    62 h-index

    413 publications

    31.9K citations

  6. Medical College of Wisconsin

    Milwaukee, United States

    61 h-index

    364 publications

    39.4K citations

  7. Istituto di Chimica Biomolecolare

    Catania, Italy

    60 h-index

    208 publications

    38.1K citations

  8. University of California, Irvine

    Irvine, United States

    60 h-index

    280 publications

    45.2K citations

1–8 of 2.7K

Venues

  1. Journal of Neuroscience

    162 publications · 23K citations

    90

    h-index

  2. British Journal of Pharmacology

    BJP · 136 publications · 13.7K citations

    65

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 66 publications · 13.3K citations

    58

    h-index

  4. PLoS ONE

    119 publications · 6.9K citations

    50

    h-index

  5. Journal of Biological Chemistry

    JBC · 57 publications · 6.9K citations

    45

    h-index

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