Mark J. Mulvihill

Discovery of OSI-906: A Selective and Orally Efficacious Dual Inhibitor of the IGF-1 Receptor and Insulin Receptor

Mark J. Mulvihill, Andrew Cooke, Maryland Rosenfeld-Franklin et al. · Future Medicinal Chemistry · 2009 · 307 citations · Full text

Feedback Mechanisms Promote Cooperativity for Small Molecule Inhibitors of Epidermal and Insulin-Like Growth Factor Receptors

Elizabeth Buck, Alexandra Eyzaguirre, Maryland Rosenfeld-Franklin et al. · Cancer Research · 2008 · 209 citations · Full text

Small Molecule Inhibitors, Tumor Biology, Receptor Tyrosine Kinase +18

A novel, potent, and selective insulin-like growth factor-I receptor kinase inhibitor blocks insulin-like growth factor-I receptor signaling <i>in vitro</i> and inhibits insulin-like growth factor-I receptor–dependent tumor growth <i>in vivo</i>

Qunsheng Ji, Mark J. Mulvihill, Maryland Rosenfeld-Franklin et al. · Molecular Cancer Therapeutics · 2007 · 147 citations · Full text

Igf-ii Expression, Signal Transduction, Growth Hormone +14

Novel Autotaxin Inhibitor for the Treatment of Idiopathic Pulmonary Fibrosis: A Clinical Candidate Discovered Using DNA-Encoded Chemistry

John W. Cuozzo, Matthew Clark, Anthony D. Keefe et al. · Journal of Medicinal Chemistry · 2020 · 109 citations · Full text

A highly effective one-pot synthesis of quinolines from o-nitroarylcarbaldehydes

An‐Hu Li, Eilaf Ahmed, Xin Chen et al. · Organic & Biomolecular Chemistry · 2006 · 81 citations

Effective One-pot Synthesis, Engineering, Di-substituted Quinolines +7