Andrew Burchat

Pyrazolo[3,4-d]pyrimidines containing an extended 3-substituent as potent inhibitors of Lck — a selectivity insight

Andrew Burchat, David J. Calderwood, Michael Friedman et al. · Bioorganic & Medicinal Chemistry Letters · 2002 · 76 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +12

Discovery of A-770041, a src-family selective orally active lck inhibitor that prevents organ allograft rejection

Andrew Burchat, David W. Borhani, David J. Calderwood et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 75 citations · Full text

Transplantation, Organ Allograft Rejection, Medicine +9

Observations on Sn-Li exchange in α-aminoorganostannanes and the configurational stability of non-stabilized α-aminoorganolithiums

Andrew Burchat, J. Michael Chong, Sheldon B. Park · Tetrahedron Letters · 1993 · 71 citations

Non-stabilized α-Aminoorganolithiums, Sn-li Exchange, Biochemistry +4

Pyrrolo[2,3-d]pyrimidines Containing an Extended 5-Substituent as Potent and Selective Inhibitors of lck II

Andrew Burchat, David J. Calderwood, Gavin C. Hirst et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 51 citations

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9

Regioselectivity in electrophilic substitution of 5-aminoindoles and 5-aminoindolines: synthesis of pyrrolo[3,2-e]indoles and isomeric pyrrolo[2,3-f]indoles

Ganesh K.B. Prasad, Andrew Burchat, Gamini Weeratunga et al. · Tetrahedron Letters · 1991 · 26 citations

Isomeric Pyrrolo, Engineering, Natural Sciences +7