Brian R. Bettencourt

Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

Teresa Coelho, David Adams, Ana Silva et al. · New England Journal of Medicine · 2013 · 961 citations · Full text

Life Sciences, Molecular Biology, Molecular Medicine +15

A Highly Durable RNAi Therapeutic Inhibitor of PCSK9

Kevin Fitzgerald, Suellen White, Anna Borodovsky et al. · New England Journal of Medicine · 2016 · 760 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +17

Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial

Kevin Fitzgerald, Maria Frank-Kamenetsky, Svetlana Shulga‐Morskaya et al. · The Lancet · 2013 · 574 citations

Life Sciences, Biochemistry, Pharmacology +16

Comparative genome sequencing of <i>Drosophila pseudoobscura</i> : Chromosomal, gene, and <i>cis</i> -element evolution

Stephen Richards, Yue Liu, Brian R. Bettencourt et al. · Genome Research · 2005 · 508 citations · Full text

Life Sciences, Evolutionary Biology, Genetics +15

Pleiotropic Effects of Vitamin D on Osteoblast Gene Expression Are Related to the Proliferative and Differentiated State of the Bone Cell Phenotype: Dependency upon Basal Levels of Gene Expression, Duration of Exposure, and Bone Matrix Competency in Normal Rat Osteoblast Cultures*

Thomas A. Owen, Michael S. Aronow, Leesa M. Barone et al. · Endocrinology · 1991 · 350 citations

Medicine, Endocrinology, Bone Metabolism +16