Maria Frank-Kamenetsky

Author

Alnylam Pharmaceuticals (United States)

Also Known As

M Frank-Kamenetsky, M. Frank-Kamenetsky, Maria D. Frank-Kamenetsky, Maria Frank-Kamenetsky

Publications

6.5K

Citations

H-Index

Concepts

All Affiliations

Alnylam Pharmaceuticals (United States)Harvard University Massachusetts General Hospital Center for Human Genetics The University of Texas Southwestern Medical Center

About

Maria Frank-Kamenetsky is an author at Alnylam Pharmaceuticals (United States) specializing in medicine, pharmacology, and health sciences.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	4.7K
2	Health Sciences	5	5	1.6K
3	Biochemistry	5	5	1.5K
4	Engineering	3	3	1.3K
5	Natural Sciences	2	2	628

Maria Frank-Kamenetsky

Publications

6.4K

Citations

H-Index

Page 1

	Year	Citations
From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus Alanna Strong, Maria Frank-Kamenetsky, Noemi E Lee, Nature Cholesterol LocusLipid DisorderAllelic VariantMedicineGenetics	2010	1.2K
Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms Akin Akinc, William Querbes, Soma De, Molecular Therapy NanotherapeuticsEngineeringImmunologyLipid NanoparticlesMolecular Biology	2010	1.1K
Lipid-like materials for low-dose, in vivo gene silencing Kevin T. Love, Kerry P. Mahon, Christopher G. Levins, Proceedings of the National Academy of Sciences In Vivo Gene TherapyImmunologyGene DeliveryBiomedical EngineeringTherapeutics	2010	952
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates Maria Frank-Kamenetsky, Aldo Grefhorst, Norma N. Anderson, Proceedings of the National Academy of Sciences	2008	635
Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial Kevin Fitzgerald, Maria Frank-Kamenetsky, Svetlana Shulga‐Morskaya, The Lancet Metabolic SyndromeOxysterolBiochemistryCardiovascular DiseaseHealthy Volunteers	2013	571
Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists Maria Frank-Kamenetsky, Xiaoyan M. Zhang, Steve Bottega, Journal of Biology	2002	488
Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides Naoki Iwamoto, David C. Butler, Nenad Svrzikapa, Nature Biotechnology Bioorganic ChemistryBiochemistryNatural SciencesOligonucleotideDna Replication	2017	358
The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals Young-Ah Moon, Guosheng Liang, Xuefen Xie, Cell Metabolism Metabolic SyndromeBiochemistryLiver PhysiologyPhysiologyDiabetes	2012	311
Silencing of Lipid Metabolism Genes through IRE1α-Mediated mRNA Decay Lowers Plasma Lipids in Mice Jae‐Seon So, Kyu Yeon Hur, Margarite L. Tarrio, Cell Metabolism Transcriptional RegulationBiochemistryNatural SciencesLipid PeroxidationGene Expression	2012	270
IRE1α activation protects mice against acetaminophen-induced hepatotoxicity Kyu Yeon Hur, Jae‐Seon So, Vera M. Ruda, The Journal of Experimental Medicine ApoptosisCell DeathEr StressToxicological MechanismOxidative Stress	2012	148

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