John D. Lich

RIP3 Induces Apoptosis Independent of Pronecrotic Kinase Activity

Pratyusha Mandal, Scott B. Berger, Sirika Pillay et al. · Molecular Cell · 2014 · 593 citations · Full text

Cell Regulation, Pronecrotic Kinase Activity, Receptor Tyrosine Kinase +6

NLRX1 is a regulator of mitochondrial antiviral immunity

Chris B. Moore, Dan T. Bergstralh, Joseph A. Duncan et al. · Nature · 2008 · 577 citations · Full text

Mitochondrial Function, Mitochondrial Antiviral Immunity, Immunology +5

NLRP12 Suppresses Colon Inflammation and Tumorigenesis through the Negative Regulation of Noncanonical NF-κB Signaling

Irving C. Allen, Justin E. Wilson, Monika Schneider et al. · Immunity · 2012 · 544 citations · Full text

Inflammation, Mucosal Immunology, Noncanonical Nf-κb Signaling +10

Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

Philip A. Harris, Scott B. Berger, Jae Uk Jeong et al. · Journal of Medicinal Chemistry · 2017 · 464 citations · Full text

Drug Target, Immunology, Cell Death +22

Autolytic Proteolysis within the Function to Find Domain (FIIND) Is Required for NLRP1 Inflammasome Activity

Joshua N. Finger, John D. Lich, Lauren Dare et al. · Journal of Biological Chemistry · 2012 · 253 citations · Full text